Testosterone Propionate is the shortest-estered testosterone steroid. It's an injectable compound with a slower rate of release than un-esterified Testosterone, but a faster rate of release than all the rest of esterified testosterones.There are some advantages and disadvantages to the short acting ester. The major disadvantage is that users have to inject Testosterone Propionate at minimum every other day throughout the cycle to get proper results. The advantages, however, are easier control and prevention of potential side effects. Also because there is less ester per vial, there is more actual testosterone per injection, which produces better results. The Propionate ester expands Testosterone's half-life to about 4 and a half days.
Biochemistry of Testosterone Propionate
Testosterone Propionate is simply Testosterone with the Propionate ester bound it's chemical structure. The 'Propionate' is Propionic acid, but once bound to Testosterone it is known as an ester bond (or ester linkage). Propinoic acid is bonded to the 17-beta hydroxyl group on the Testosterone structure. Esterified anabolic steroids are more fat soluble, and release slowly from the injection site. The main reason for the increased half-life and release rate is because once Testosterone Propionate enters the bloodstream, enzymes work to break the bond between the ester and the testosterone, which takes a varying amount of time - depending on which ester is used. In the end enzymes remove the ester, and what is left is pure Testosterone which is free to do its work in the body. Testosterone alone with no ester bonded to it has a half-life of approximately 2 to 4 hours. When the Propionate ester is bonded to it, the half-life of Testosterone extends to about 4 and a half days.
Testosterone promotes nitrogen retention in the muscle - the more nitrogen the muscle holds the more protein it can store, and the bigger it gets. Testosterone also increases the body's IGF-1 levels. IGF-1's principal role is to coordinate growth and metabolism. IGF-I is highly dependent on growth hormone to complement it's growth promoting activity.
Testosterone Propionate has been vastly used for medical treatments shortly after its release in the 1930's. Among other it was used for treatment for male androgen deficiency (andropause or hypogonadism), treatment for sexual dysfunction, and treatment for menopause, treatment for chronic dysfunctional uterine bleeding (menorrhagia), treatment for endometriosis. Later on testosterone would only be used for male patients.
Testosterone Propionate is one of the most popular anabolic steroids even today - 80 years after it's invention. It is widely used by bodybuilders and athletes for the purpose of physique and performance enhancement. Testosterone itself is considered the most natural and safest anabolic steroid a person can use. The Propionate ester is suggested for any first time steroid user.
The most common dosage for Testosterone Propionate is:
50 to 100mg every day
50 to 100mg every 2nd day
Every 3rd day should be the absolute minimum because that's near the border of Propionate activity timespan.
Cook recipes for Testosterone Propionate: 10 grams 100 ml @ 100mg/ml
10 grams powder
72.5 ml sesame oil
5ml Benzyl Alcohol = 5%
15ml Benzyl Benzoate = 15%
Syringes 3cc & 5/10cc
18 or 20 gauge needles
Whatman sterile filter
Words from Experienced Bodybuider:
Testosterone Propionate has a much sorter life cycle than either the Cypionate and Enthanate! However, because of this reason it is even more anabolic with shots every other day making the beginner Bodybuilder shy away from its use ! Testosterone Propionate is the only steroid you can use leading up to the pre contest phase of a competition because it holds the least amount of water! It also helps to maintain the volume in your muscles through protein synthesis while on a low calorie pre- contest diet!