Mestanolone

Description

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Mestanolone

Mestanolone (Proviron) is the 17a-methylated version It is an orally bioavailable androgenic steroid that is highly androgenic while only slightly anabolic. It is incapable of aromatization and is not an agonist of the progesterone receptor. Dosages range from 10mg to 30mg a day for males. Women should avoid Mestanolone for it is very androgenic. Long term use, more than 12 weeks should be avoided do to hepatoxicity. Since Mestanolone is unable to convert to estrogen, it is very useful during cutting phases or when one wishes to avoid excess weight gain. Again it's stacked with Masteron and Halotestin even Testosterone a Propionate the final weeks of a cutting phase!

Below shows the average results of Mestanolone:

Mestanolone for bodybuilding

Mestanolone, also known as methyldihydrotestosterone (MDHT), is a synthetic anabolic steroid that is structurally similar to dihydrotestosterone (DHT).

Mestanolone is considered to be a relatively weak anabolic steroid, it is not as powerful as other steroids such as testosterone, Trenbolone, or Deca-Durabolin. It may have some benefit for bodybuilders looking to increase muscle mass and strength, but it's not considered as effective as other steroids for this purpose. Additionally, because of its chemical structure, Mestanolone is more androgenic, meaning that is more likely to cause side effects such as acne, hair loss, and prostate enlargement.

Benefits of Mestanolone

Mestanolone is an anabolic steroid that is believed to have a variety of potential benefits for athletes and bodybuilders. Some of the potential benefits of mestanolone include increased muscle mass, improved strength and endurance, and enhanced athletic performance. Additionally, mestanolone may also be used to help treat certain medical conditions, such as muscle wasting and osteoporosis. 

Mestanolone mechanism of action

Mestanolone is a synthetic anabolic steroid that is structurally similar to the male hormone testosterone. Like testosterone, mestanolone binds to and activates the androgen receptor (AR) in target tissues, leading to the activation of specific genes involved in muscle growth and development.

When mestanolone binds to the AR, it initiates a cascade of molecular events that ultimately lead to the activation of transcription factors, which then bind to DNA and regulate the expression of genes that control muscle growth and development. This increased expression of genes leads to an increase in protein synthesis, which results in muscle growth and increased strength.

Mestanolone also has a direct effect on protein synthesis by inhibiting the action of the enzyme 3-beta-hydroxysteroid dehydrogenase, which is responsible for the conversion of DHEA to estrogen. By inhibiting this enzyme, mestanolone reduces the conversion of DHEA to estrogen, which leads to an increase in muscle mass and strength.